Ultrasound is used for breast cancer detection as a technique complementary to mammography, the standard screening method. Current practice is based on reflectivity images obtained with conventional instruments by an operator who positions the ultrasonic transducer by hand over the patient’s body. It is a non-ionizing radiation, pain-free and not expensive technique that provides a higher contrast than mammography to discriminate among fluid-filled cysts and solid masses, especially for dense breast tissue. However, results are quite dependent on the operator’s skills, images are difficult to reproduce, and state-of-the-art instruments have a limited resolution and contrast to show micro-calcifications and to discriminate between lesions and the surrounding tissue. In spite of their advantages, these factors have precluded the use of ultrasound for screening. This work approaches the ultrasound-based early detection of breast cancer with a different concept. A ring array with many elements to cover 360◦ around a hanging breast allows obtaining repeatable and operator-independent coronal slice images. Such an arrangement is well suited for multi-modal imaging that includes reflectivity, compounded, tomography, and phase coherence images for increased specificity in breast cancer detection. Preliminary work carried out with a mechanical emulation of the ring array and a standard breast phantom shows a high resolution and contrast, with an artifact-free capability provided by phase coherence processing.
Breast cancer screening is based on X-ray mammography, while ultrasound is considered a complementary technique with improved detection in dense tissue. However, breast cancer screening requires a technique that provides repeatable results at the inspection interval which cannot be achieved with manual breast exploration. During the last years there have appeared several approaches to overcome this limitation by means of automated ultrasonic tomography performed with motorized probes or with a large set of array transducers. This work addresses these problems by considering a quite simple and low-cost arrangement, formed with a ring of conventional medical-grade array probes which are multiplexed to the electronics to build Full Angle Spatially Compounded (FASC) images. The work analyzes the performance of such arrangement in terms of resolution and isotropy, showing by numerical modelling and experimentally that it provides high resolution and homogeneity in the whole imaged region. The implementation of this technique would provide more than one circular FASC per second and a whole breast volume image in 1–2 minutes with conventional technology, a process fast enough to be clinically useful. Moreover, the automated technique is repeatable and can be used by the clinician to perform immediately the diagnosis without requiring additional data processing.
Background: Unhealthy diet and cooking method used may infl uence the risk of breast cancer (BC), but there is only limited evidence with regard to benign breast disease (BBD). The aim of this study was to assess a relationship between cooking technique, especially fried to boiled meals ratio in the diet, and the risk of BC and BBD in a group of Polish women. Material and methods: A case-control study involving 34 BC cases, 81 BBD cases and 122 healthy controls was conducted between July 2007 and November 2011. All the women were asked about their nutritional habits, especially the way of preparing meat and fi sh dishes. Th en the ratio of fried to boiled meals was calculated. Results: High fried to boiled ratio was associated with increasing risk of BBD, but not BC. Women consuming fried dishes more oft en than boiled dishes had elevated risk of BBD: OR = 3.04 and OR = 3.65 for the second and the third tertile, respectively. Adjustment for the other confounders only slightly altered this relationship. Conclusion: Women who preferred frying as a cooking technique had increased risk of benign breast disease, but not breast cancer. Th ere is a need of more precise investigation to confi rm this association.