The brain is subject to damage, due to ageing, physiological processes
and/or disease. Some of the damage is acute in nature, such as strokes;
some is more subtle, like white matter lesions. White matter lesions or
hyperintensities (WMH) can be one of the first signs of micro brain
damage. We implemented the Acoustocerebrography (ACG) as an easy to use
method designed to capture differing states of human brain tissue and
the respective changes.
Aim: The purpose of the study is to compare the efficacy of ACG and
Magnetic Resonance Imaging (MRI) to detect WMH in patients with
clinically silent atrial fibrillation (AF).
Methods and results: The study included 97 patients (age 66.26 ± 6.54
years) with AF. CHA2DS2-VASc score (2.5 ±1.3) and HAS BLED (1.65 ± 0.9).
According to MRI data, the patients were assigned into four groups
depending on the number of lesions: L0 – 0 to 4 lesions, L5 – 5 to 9
lesions, L10 – 10 to 29 lesions, and L30 – 30 or more lesions. Authors
found that the ACG method clearly differentiates the groups L0 (with 0–4
lesions) and L30 (with more than 30 lesions) of WMH patients. Fisher’s
Exact Test shows that this correlation is highly significant (p < 0:001).
Conclusion: ACG is a new, easy and cost-effective method for detecting
WMH in patients with atrial fibrillation